Ester-Urethane Interchange Reaction

Electrospun Poly(ester-Urethane)- and Poly(ester-Urethane-Urea) Fleeces as Promising Tissue Engineering Scaffolds for Adipose-Derived Stem Cells

An irreversible loss of subcutaneous adipose tissue in patients after tumor removal or deep dermal burns makes soft tissue engineering one of the most important challenges in biomedical research. The ideal scaffold for adipose tissue engineering has yet not been identified though biodegradable polymers gained an increasing interest during the last years. In the present study we synthesized two ...

Chemoenzymatic Synthesis and Chemical Recycling of Poly(ester-urethane)s

Novel poly(ester-urethane)s were prepared by a synthetic route using a lipase that avoids the use of hazardous diisocyanate. The urethane linkage was formed by the reaction of phenyl carbonate with amino acids and amino alcohols that produced urethane-containing diacids and hydroxy acids, respectively. The urethane diacid underwent polymerization with polyethylene glycol and α,ω-alkanediols and...

biodegradation of poly(ester urethane)s by bacillus subtilis

polyurethanes (purs) are polymers that can be generated by a step-growth polyadditionreaction of diisocyanates with polyols. the number of well-developed chemical procedures applicable to theirmanufacture, and the diversity of chemical structures in which polyurethanes can be built, account for thewidespread use of these materials in the last few decades for both domestic and technical applicat...

Poly(ester-urethane) scaffolds: effect of structure on properties and osteogenic activity of stem cells.

The present study aimed to investigate the effect of structure (design and porosity) on the matrix stiffness and osteogenic activity of stem cells cultured on poly(ester-urethane) (PEU) scaffolds. Different three-dimensional (3D) forms of scaffold were prepared from lysine-based PEU using traditional salt-leaching and advanced bioplotting techniques. The resulting scaffolds were characterized b...

Healing of Rat Calvarial Defects With Nanohydroxyapatite/Poly(Ester- urethane) Scaffolds Loaded With rhBMP-2